Chemist no. 151 of 350 · Biochemistry

Bruce Merrifield

1921-2006United StatesNobel Chemistry 1984

Solid-phase peptide synthesis

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The discovery, explained

Bruce Merrifield: Building Proteins on a Bead

How Bruce Merrifield invented solid-phase peptide synthesis: resin, Boc protection, DCC coupling, TFA deprotection and HF cleavage. Notes for JAM, NET, GATE.

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Biography

Bruce Merrifield: The Chemist Who Taught Machines to Build Peptides

Life of Bruce Merrifield (1921-2006): Texas-born, Californian-raised chemist at UCLA and Rockefeller, inventor of solid-phase peptide synthesis, Nobel Prize 1984.

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Academic lineage

Documented doctoral, postdoctoral and teaching links. Dashed chips are teachers outside the 350 chemists listed here.

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