ABC26OR0391 · Reagents Reaction Mechanisms and Named Reactions
Subject: Organic Chemistry · Chapter: Reagents Reaction Mechanisms and Named Reactions · Topic: Reagents, Reaction Mechanisms & Named Reactions – General · Exam: CSIR-NET DEC 2018 · Marks: 2 · Difficulty: Medium
The structures of products A and B formed in the Edman degradation of dipeptide are-
(a)B =
(b)B =
(c)A =B =
(d)A =B =
Answer
Answer (as printed): D
Explanation
The mechanism of the reaction is shown below: Edman degradation method is used for N-terminal analysis of protein. Since this method can label and cleave the peptide from N-terminal and forms corresponding and forms corresponding phenylthiohydonation derivative of amino acid.
Explanation as extracted from the printed page; notation may be imperfect.