Chemist no. 164 of 350 · Biochemistry

Michael Smith

1932-2000CanadaNobel Chemistry 1993

Site-directed mutagenesis

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The discovery, explained

Michael Smith and Site-Directed Mutagenesis: Editing a Protein One Amino Acid at a Time

How Michael Smith developed oligonucleotide-directed site-directed mutagenesis to change proteins at chosen positions, winning the 1993 Nobel Prize in Chemistry.

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Biography

Michael Smith: Complete Life and Legacy of the Pioneer of Protein Engineering

Life of Michael Smith (1932-2000), the English-born Canadian biochemist who shared the 1993 Nobel Prize in Chemistry for site-directed mutagenesis.

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