Q14 · CSIR-NET Chemistry, December 2012

Paper: CSIR-NET December 2012 · Subject: Organic Chemistry · Chapter: Natural Products · Topic: Amino Acids Peptides · Marks: 2 · Difficulty: Medium

A tripeptide gives the following products on Edman degradation. Question structure 1 of 2, ABC26OR0080 + Question structure 2 of 2, ABC26OR0080 The tripeptide is
(a)Phe-Ala-Gly
(b)Phe-Gly-Ala
(c)Ala-Gly-Phe
(d)Gly-Ala-Phe
Answer
Answer: A ✓ checked by 4AB · confidence high
Explanation
Edman degradation removes the N-terminal residue as its PTH derivative; here it is phenylalanine (benzyl side chain). The remaining dipeptide is Ala-Gly, so the tripeptide is Phe-Ala-Gly (a).

Study loop for Natural Products

1. Practise the PYQsPrevious-year questions, with answers

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