Q25 · CSIR-NET Chemistry, June 2017

Paper: CSIR-NET June 2017 · Subject: Inorganic Chemistry · Chapter: Bioinorganic Chemistry · Topic: Metal Toxicity Medicine · Marks: 2 · Difficulty: Easy

Consider the following statements for deoxy-hemerythrin and deoxy-hemocyanin: A. they are involved in $\mathrm{O}_2$ transport in biological systems B. they contain two metal ions in their active site C. active site metal centres are bridged by amino acid residues D. they prefer to bind only one $\mathrm{O}_2$ per active site The correct statements are
(a)A, B and D
(b)A, C and D
(c)B, C and D
(d)A and C
Answer
Answer: A ✓ checked by 4AB · confidence high
Explanation
Both transport O₂, both have two metal ions at the active site, and both bind one O₂ per site. Only hemerythrin's irons are bridged by amino-acid carboxylates; the two coppers of hemocyanin have no bridging residue. A, B and D (a).

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