Choose the correct set of statements for cis-platin.(A) It can be prepared from $\mathrm{K_2[PtCl_4]}$.(B) It can be prepared from $[\mathrm{Pt(NH_3)_4Cl_2}]$.(C) In its preparation, the observed trans effect for $\mathrm{Cl^{-}}$ is greater than that of $\mathrm{NH_3}$(D) In blood it stays in equilibrium with cis-$[\mathrm{Pt(NH_3)_2Cl(H_2O)}]^{+}$(E) In DNA strand, it binds to two adjacent cytosine bases.The correct set is
(a)A, C and D
(b)A, C, D and E
(c)B, C and D
(d)B, C, D and E
Answer
Answer: A ✓ checked by 4AB · confidence high
Explanation
Cisplatin is made from K₂[PtCl₄], using the greater trans effect of Cl⁻ over NH₃. In blood it is in equilibrium with the aqua species. [Pt(NH₃)₄]²⁺ gives the trans isomer, and in DNA it binds two adjacent guanines, not cytosines. A, C and D (a).