Paper: CSIR-NET June 2019 · Subject: Inorganic Chemistry · Chapter: Bioinorganic Chemistry · Topic: Bioinorganic Chemistry – General · Marks: 2 · Difficulty: Medium
Consider the following transformation, reactions in the context of co-enzyme $mathrm{B_{12}}$(A) 1,2-Carbon shift(B) Hydration of $mathrm{CO_2}$(C) Benzene to phenol(D) dimethyl sulfide to demethyl sulfoxideThe correct statement(s) for co-enzyme $mathrm{B_{12}}$ is/are
(c)B, C only
(d)A only
(a)A, C, D
(b)A, B only
Answer
Answer: D ✓ checked by 4AB · confidence medium
The source book printed no answer; this one was worked out and checked — see the explanation.
Explanation
Coenzyme B₁₂ (adenosylcobalamin) enzymes catalyse radical 1,2-carbon-skeleton rearrangements (e.g. methylmalonyl-CoA mutase); CO₂ hydration is Zn (carbonic anhydrase), arene hydroxylation and S-oxidation are Fe/Cu or flavin chemistry — A only.