The major product in A and B in the following reaction sequence is: A POCl₃ (excess) B · ABC26OR0404
Subject: Organic Chemistry · Chapter: Reagents, Reaction Mechanisms & Named Reactions · Topic: Reagents, Reaction Mechanisms & Named Reactions – General · Exam: CSIR NET 2019 · Marks: 2 · Difficulty: Medium
The major product in A and B in the following reaction sequence is: 
A 
$\mathrm{POCl_3}$ (excess) B
A $\mathrm{POCl_3}$ (excess) B(a)A = 
B = 
B = (b)A = 
B = 
B = (c)A = 
B = 
B = (d)A = 
B = 
B = Answer
Answer: D ✓ checked by 4AB · confidence high
Explanation
With one equivalent of Vilsmeier reagent the indole C-3 (most nucleophilic) is formylated (A); excess reagent also formylates the free α-position (C-5) of the furan (B) — (d).
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