The major product in the following reaction is THF, r.t · ABC26OR0322
Subject: Organic Chemistry · Chapter: Reagents, Reaction Mechanisms & Named Reactions · Topic: Named Reactions · Exam: CSIR NET DEC 2016 · Marks: 2 · Difficulty: Medium
The major product in the following reaction is 
THF, r.t
THF, r.t(a)
(b)
(c)
(d)
Answer
Answer: A ✓ checked by 4AB · confidence high
Explanation
2-Pyridyllithium is transmetallated to the zinc reagent and a Negishi coupling replaces the C-6 bromine; the OMe groups and the amide are untouched, giving the 2,2′-bipyridine (a).
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