The absolute configurations of the two chiral centers in the following molecule are · ABC26OR0744
Subject: Organic Chemistry · Chapter: Stereochemistry · Topic: Stereochemistry – General · Exam: GATE 2000-2022 · Marks: 2 · Difficulty: Hard
The absolute configurations of the two chiral centers in the following molecule are 
(a)2(R), 3(S)
(b)2(R), 3(R)
(c)2(S), 3(S)
(d)2(S), 3 (R)
Answer
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Explanation
C-2: Br > COOH > C-3 runs anticlockwise with H on a horizontal bond, so 2R. C-3: OH > C-2 (bears Br) > CN runs clockwise with H horizontal, so 3S (a).
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