Q26 · CSIR-NET Chemistry, June 2016

Paper: CSIR-NET June 2016 · Subject: Inorganic Chemistry · Chapter: Bioinorganic Chemistry · Topic: Bioinorganic Chemistry – General · Marks: 2 · Difficulty: Medium

In human body cis- platinhydrolyzes to diaqua complex and modifies the DNA structure by binding to
(a)N-atom of guanine base
(b)N-atom of adenine base
(c)O-atom of cytosine base
(d)O-atom of thymine base
Answer
Answer: A ✓ checked by 4AB · confidence high
Explanation
Cisplatin binds N7 of guanine (a).

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