In the catalytic cycle of Cytochrome P₄₅₀, the generation of [(porphyrin)+FeIV(O)] from… · ABC26IN0916
Subject: Inorganic Chemistry · Chapter: Bioinorganic Chemistry · Topic: Bioinorganic Chemistry – General · Exam: CSIR NET DEC 2019 · Marks: 2 · Difficulty: Medium
In the catalytic cycle of Cytochrome $\mathrm{P_{450}}$, the generation of $[(\mathrm{porphyrin})+\mathrm{Fe^{IV}}(\mathrm{O})]$ from $[(\mathrm{porphyrin})\mathrm{Fe^{III}}(\mathrm{OOH})]$ involves
(a)One electron oxidation of $[(\mathrm{porphyrin})\mathrm{Fe^{III}}(\mathrm{OOH})]$
(b)Formation of the intermediate $[(\mathrm{porphyrin})\mathrm{Fe^{IV}}(\mathrm{OH})]$
(c)Homolytic O-O cleavage of $[(\mathrm{porphyrin})\mathrm{Fe^{IV}}(\mathrm{OOH})]$
(d)Heterolytic O-O cleavage of $[(\mathrm{porphyrin})\mathrm{Fe^{III}}(\mathrm{OOH})]$
Answer
Answer: D ✓ checked by 4AB · confidence high
Explanation
Heterolytic O–O cleavage of protonated Fe(III)–OOH forms compound I (d).